Prevalence of Specific Helicobacter Pylori CagA, VacA, IceA, UreC Genotypes and its Clinical Relevance in the Patients with Acid-Peptic Diseases
نویسندگان
چکیده
منابع مشابه
Prevalence of Helicobacter pylori vacA, cagA, and iceA Genotypes in Cuban Patients with Upper Gastrointestinal Diseases
Virulence factors of Helicobacter pylori can predict the development of different gastroduodenal diseases. There are scarce reports in Cuba about H. pylori isolates genotyping. The aim of the present investigation was to identify allelic variation of the virulence genes vacA, cagA, and iceA in sixty-eight patients diagnosed as H. pylori positive by culture. In seven out of 68 patients, strains ...
متن کاملClinical relevance of the cagA, vacA and iceA genotypes of Helicobacter pylori in Brazilian clinical isolates.
Infection with Helicobacter pylori strains harboring determinants of pathogenicity may lead to a strong inflammatory response in gastric mucosa. In this work, we examined the frequency of the cagA, vacA and iceA genotypes in H. pylori strains isolated from Brazilian patients and correlated these with the clinical manifestations. H. pylori was isolated from 165 patients [30 with non-ulcer dyspep...
متن کاملPrevalence of Helicobacter pylori vacA, cagA and iceA genotypes and correlation with clinical outcome
The aim of this study was to assess the genetic status of cagA, vacA subtype and iceA genotypes of Helicobacter pylori and the relationship with upper gastrointestinal diseases in Northeast China. Gastric biopsies were obtained from 378 patients with upper gastrointestinal diseases and 197 samples were used. The cagA, vacA alleles and iceA genotypes were determined by polymerase chain reaction....
متن کاملPrevalence of Helicobacter pylori vacA, cagA and iceA genotypes in Nigerian patients with duodenal ulcer disease.
Distinct virulence factors of Helicobacter pylori have been associated with clinical outcome of the infection; however, considerable variations have been reported from different geographic regions. Data on genotypes of African H. pylori isolates are sparse. The aim of this study was to determine the prevalence of specific genotypes of H. pylori in Nigerian patients with duodenal ulcer and non-u...
متن کاملClinical Relevance of vacA, cagA, and iceA Genotypes of Helicobacter pylori
Introduction: Helicobacter pylori infection is associated withvariable clinical outcomes, including gastroduodenal diseases, and genetic factors may be relevant in this process. The aim of this study was to investigate any association between the H. pylori genotypes and the clinical out come in patients diagnosed with gastrointestinal diseases. Methods: Antral gastric biopsy specimens were coll...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
سال: 2017
ISSN: 2249-782X
DOI: 10.7860/jcdr/2017/27812.10457